Publications

Peer-Reviewed Publications


Rethinking Medical LLM Hallucinations: A System-Level Survey

In pressArtificial Intelligence in Medicine

A. Matthews, V. Vankadaru, T. Roosta, P. Passban

A survey of hallucination in medical LLMs covering definitions, benchmarks, detection, and mitigation. It argues that hallucination is a structural property of probabilistic generation and should be treated as a system-level risk management problem.

Under Review and In Preparation


Potential for Age-Based Bias in AI-Informed Neurosurgical Decision-Making: A Sociodemographic Subgroup Assessment Approach for Open-Source Glioma Molecular Subtype Classifiers

In reviewUCSF, with the Departments of Neurological Surgery and Radiology

E. S. Danthinne, V. Vankadaru, H. Miao, P. Nedelec, A. Rauschecker, R. Morshed, A. Molinaro, M. Sushil

External validation of three published glioma subtype classifiers on 3,380 UCSF patients, with subgroup tests powered by an LLM labeling pipeline over 9,377 pathology reports. Errors concentrate by age: specificity 54% for IDH-wildtype patients under 40 versus 80% at 55 and older, a difference AUROC does not show.

Benchmarking Somatic Mutation Representations for Cancer Typing and HRD Prediction

In reviewUniversity of Maryland Institute for Health Computing

A. Ge, V. Vankadaru, X. Liu, J. Almeida, J. B. Balasubramanian, B. A. Maron

We introduce Bio MAF v4, a 948-feature interpretable representation of a tumor’s somatic mutations, and benchmark it against mutational signatures and a MuAt transformer trained from scratch on 8,800 TCGA tumors across 20 cancer types. The feature table outperforms the transformer (0.738 vs 0.528 balanced accuracy) and transfers to 913 PCAWG tumors.